Erik ten Hag has named his starting eleven to face West Ham knowing a win would take the Red Devils a place above Chelsea in the Premier League.
Manchester United welcome West Ham to Old Trafford in the Premier League.
Ten Hag’s side comfortably beat FC Sheriff 3-0 in the Europa League on Thursday night and will be hoping to continue their winning form versus the Hammers.
The attention is back on the Premier League as United look to finish in the top four after missing out last season.
David de Gea starts between the sticks in front of a defence which consists of Diogo Dalot, Lisandro Martinez, Harry Maguire and Luke Shaw.
Club captain Maguire makes his first Premier League start since the infamous 4-0 loss at Brentford.
Casemiro and Christian Eriksen are in charge of controlling the game in the middle, with help from Bruno Fernandes in the final third.
Cristiano Ronaldo leads the attack with Marcus Rashford and Anthony Elanga.
Manchester United XI: De Gea; Dalot, Maguire, Martinez, Shaw; Casemiro, Eriksen, Fernandes; Rashford, Ronaldo, Elanga.