Ole Gunnar Solskjaer has included Edinson Cavani and Scott McTominay in his Manchester United starting lineup to face Arsenal at the Emirates Stadium.
United are unbeaten in 17 away matches but need a response in North London after Wednesday’s shock defeat to bottom placed Sheffield United at Old Trafford.
Arsenal, meanwhile, have discovered some form under Mikel Arteta and are now without a defeat in six Premier League games.
Solskjaer has made five changes from his side that fell to an improbable 2-1 defeat to the Blades.
As reported by Stretty News earlier in the day, Edinson Cavani returns to lead the line with the out-of-sorts Anthony Martial dropping to the bench.
Marcus Rashford retains his place and will support Cavani alongside Paul Pogba in what appears to be a triple-pronged attack.
Scott McTominay starts in a familiar midfield axis with Fred, protecting the central defensive partnership of captain Harry Maguire and the returning Victor Lindelof.
Lindelof started on the bench against Sheffield United in midweek but comes in for Axel Tuanzebe who faltered.
Elsewhere, Luke Shaw will be hoping to continue his fine form at left-back and Aaron Wan-Bissaka continues on the right.
A strong United bench includes Mason Greenwood, Donny van de Beek and Nemanja Matic.
Manchester United lineup to face Arsenal: De Gea, Wan-Bissaka, Maguire, Lindelof, Shaw, McTominay, Fred, Fernandes, Pogba, Rashford, Cavani
𝐈𝐭'𝐬 𝐭𝐢𝐦𝐞 𝐟𝐨𝐫 𝐭𝐞𝐚𝐦 𝐧𝐞𝐰𝐬 📣
Ole makes 5️⃣ changes to today's #MUFC starting XI 👇
— Manchester United (@ManUtd) January 30, 2021
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Arsenal: Fred and Cavani start