Jose Mourinho made eight changes from the weekend as Sergio Romero, Antonio Valencia, Eric Bailly, Marcos Rojo, Marouane Fellaini, Andreas Pereira, Fred and Paul Pogba all come in for Manchester United.
The bench has a mixture of youth and experience: Lee Grant, Ashley Young, James Garner, Ander Herrera, Jesse Lingard, Mason Greenwood, Marcus Rashford.
READ MORE: (Video) Man Utd U19s come from behind to beat Valencia 2-1 in UEFA Youth League
As per usual, United fans have been posting their initial reaction to the team news on social media. Some are happy to see Garner and Greenwood on the bench, while others are pleased to see the return of Andreas Pereira to the line-up.
The Brazil international started the season in the team but was quickly replaced when Nemanja Matic returned to match fitness after representing Serbia at the World Cup.
Finally, Andreas pic.twitter.com/677jTz42UG
— Trivellato🤧 (@AisidaToni) December 12, 2018
If Greenwood comes on as a substitute with 10-15 minutes remaining, He is going to SCORE. Mark my words. 👊🏻
— ➆ (@MysticalAlexis) December 12, 2018
Good to see @andrinhopereira in the staring 11 he’s a good player he needs to be given more of a chance come on @ManUtd #MUFC #MUFC_Family #UCL
— Michael Sweetman (@united1992) December 12, 2018
Pogba, Bailly AND Periera 🤞🔥
— ♡#MUFC Girl♡ (@reshmikasingh) December 12, 2018
I don’t care about anything other than Andreas Pereira staring 😊✨
— Laaaiqahhhh (@Laaiqah07) December 12, 2018
I’m interested to see what formation United play.
José previousily persisted with Andreas Pereira in front of the back four.
Will he play on the left wing or is the midfield four a diamond? 🤔#MUFC #UCL— 𝑺𝒉𝒊𝒗𝒆𝒏🔰 (@Shiven_MUFC) December 12, 2018
Andreas Pereira starts 💥💥💥💥 pic.twitter.com/GCcpDby5N4
— – uche (@_thebornsinner) December 12, 2018
Andreas Pereira finally back…
— MUFC Fans (@mufcfans) December 12, 2018
Would like to see the Greenwood kid given a chance tonight
— SN (@Ronynjege) December 12, 2018
Greenwood & Garner on the bench well deserved #mufc
— Azza aka (@AaronCmufc) December 12, 2018
Great to see Greenwood & Garner on the bench. Hopefully more than a token gesture as there’s a huge amount of home grown talent waiting to step up
— The Man From Del Monte (@jonsbrooks1984) December 12, 2018
So for months our supporters saying please play Fred Andreas and Pogba. The world is your oyster boys, no pressure game let’s see what you got.
— MUFC_Loyal (@LoyalMufc) December 12, 2018